Table 1.
Clinical and demographic data including follow-up data on the patients. Four of the RRMS patients had transitioned to SPMS, one of whom was deceased.
| Cohort | Controls | RRMS | SPMS |
| n | 10 | 30 | 16 |
| On treatment, n | 0 | 15 | 1 |
| Age *, mean (±SD) | 39 (±13.1) | 39 (±10.6) | 58 (±9.3) |
| Female/Male | 6/4 | 21/9 | 10/6 |
| EDSS *, median(range) | n/a | 2.0 (0–7.5) | 5.5 (3.0–7.5) |
| Disease duration *, median (range) | n/a | 92 (0.5–364) | 283 (109–538) |
| Follow up | RRMS | SPMS | |
| n | 27 | 13 | |
| ΔEDSS, median (range) | 0.0 (−3.5–3.0) | 1.5 (0–4.0) | |
| Time interval in months, mean (±SD) | 67.6 (±15.4) | 54.8 (±18.6) | |
| Transitioned, n | 4 | n/a | |
| Deceased, n | 1 | 0 |
* Signifies a significant difference between SPMS and RRMS patients. EDSS: Expanded Disability Status Score; n/a: not applicable.