C57BL/6 gal-1−/− have a decreased bone mass. (A) Representative 3D-reconstructions of distal femurs. CTAn analysis was performed and (B) cortical thickness (Ct;Th), (C) cortical bone volume (Ct.BV/TV), (D) trabecular bone volume (Tb.BV/TV), (E) trabecular thickness (Tb.Th), (F) trabecular separation (Tb.Sp), (G) trabecular number (Tb.N), (H) polar mean moment of inertia (MMI(polar)), (I) periosteal perimeter, (J) endosteal perimeter and (K) trabecular connective density (Conn.Dn) are reported here. Data shown are the mean +/− standard error of three mice and all results shown are representative of three biologically independent experiments. * p < 0.05; ** p < 0.01; *** p < 0.001.