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. 2019 Feb 22;8(2):270. doi: 10.3390/jcm8020270

Figure 1.

Figure 1

Flowchart showing the proposed soluble ST2 (sST2) aided management of patients with dyspnea and elevated natriuretic peptides (NPs). In patients with dyspnea and elevated NPs, sST2 levels can help to identify 3 classes of patients. If sST2 < 35 ng/mL, the diagnosis of acute decompensated heart failure (ADHF) is unusual. In patients with 35 ≤ sST2 ≤ 70 ng/mL, ADHF is more common but mild to moderate. If sST2 > 70 ng/mL, ADHF is fairly common, requiring hospitalization and anti-remodeling therapies. Suggested actions for each class of patients are shown in the panels below.