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. 2019 Jan 23;7(2):28. doi: 10.3390/microorganisms7020028

Table 2.

Biofilm formation inhibition exerted by compounds 1, 3, 4, and 8. Each molecule was added at its relative MIC and 2× MIC (µg/mL) values during the biofilm formation of the different pathogens; the inhibition percentages were determined after spectrophotometer reader at 570 nm.

Microbial Strains 1 3 4 8
Biofilm Inhibition Biofilm Inhibition Biofilm Inhibition Biofilm Inhibition
MIC MIC 2× MIC MIC MIC 2× MIC MIC MIC 2× MIC MIC MIC 2× MIC
E. coli ATCC 35218 8 68.3% BE 64 97.6% BE 16 1.7% 48.1% 128 54.1% 92.0%
S. aureus ATCC 43387 8 82.2% BE 128 BE ND 128 56.6% BE 128 34.9% 62.9%
E. faecalis ATCC 29212 32 BE ND 128 BE ND 128 BE ND 128 BE ND
P. aeruginosa ATCC 9027 64 0.5% 0.9% 128 7.8% BE 128 4.8% BE 128 7.1% BE
K. pneumoniae 6/4 8 40.0% 83.7% 128 BE ND 32 64.7% 96.6% 128 65.8% 98.7%
C. albicans ATCC 10231 64 BE ND 128 34.6% BE 32 14.6% 40.9% 128 BE ND

BE, bactericidal effect: biomass was not determined by spectrophotometer reader (570 nm) because no bacterial growth was visible. in the wells (see also Figure S1); ND: not determined because already bactericidal at MIC value.