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. 2019 Feb 8;11(2):198. doi: 10.3390/cancers11020198

Figure 2.

Figure 2

Gene transduction of Ad5 and Ad5/3 in non-human cells. Mouse, hamster, canine, and porcine cells along with human controls were infected with replication-deficient Luciferase expressing vectors, Ad5CMV-Luc and Ad5/3CMV-Luc. Luciferase activity was determined 2 days post infection. Infection with Ad5 efficiently transduced all non-human cells. Compared to Ad5, Ad5/3 gene transfer was significantly lower in rodent and canine cells but higher in porcine cells (* p < 0.05, ** p < 0.005, *** p < 0.001 Denotes significance to Ad5 infected cells).