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. 2019 Feb 3;8(2):177. doi: 10.3390/jcm8020177

Table 2.

Correlation of plasma levels of LDL-C, L5, L5%, or LOX-1 expression with the extent of subclinical atherosclerosis and 10-year CVD risk (QRISK-2) scores in RA patients (n = 64).

Plasma LDL-C Levels LDLR Expression Plasma
L5%
Plasma
L5 Levels
LOX-1 Expression
Right ccIMT, mm 0.217 0.150 0.537 b 0.611 b 0.457 b
Left ccIMT, mm 0.245 0.223 0.457 b 0.540 b 0.507 b
QRISK-2 scores 0.072 0.244 0.256 a 0.278 a 0.339 a
Framingham score (%) 0.160 0.336a 0.107 0.188 0.251
Atherogenic index 0.635 b 0.294 a −0.024 0.281 a 0.318 a
LDL-C levels - 0.181 −0.107 0.298 a 0.117
LDLR expression 0.181 - 0.102 0.182 0.298 a
Plasma L5% −0.107 0.102 - 0.895b 0.497 b
Plasma L5 levels 0.298 a 0.182 0.895 b - 0.588 b
LOX-1 expression 0.117 0.298 a 0.497 b 0.588 b -
Body mass index 0.056 0.108 0.300 a 0.317 a 0.458 b
DAS28 at entry −0.225 −0.015 0.361 b 0.254 a 0.166

ap < 0.05 and b p < 0.01, determined by using the nonparametric Spearman’s correlation test. Atherogenic index corresponds to the ratio of total cholesterol/high-density lipoprotein cholesterol. RA: Rheumatoid arthritis; ccIMT: Common carotid artery intima-media thickness; LDLR: LDL-C receptor; LOX-1: Lectin-like oxidized low-density lipoprotein recptor-1; DAS28: Disease activity score for 28-joints.