Table 2.

Relationship between white matter changes and the severity of Alzheimer’s disease.

	AD
Fazekas Scale		Very Mild Dementia CDR 0.5	Mild Dementia CDR 1	Moderate Dementia CDR 2
Periventricular white matter changes	0	35 (27.3%)	54 (19.1%)	14 (15.6%)
	1	44 (34.4%)	94 (33.2%)	18 (20.0%)
	2	22 (17.2%)	69 (24.4%)	23 (25.6%)
	3	27 (21.1%)	66 (23.3%)	35 (38.9%)
Deep white matter changes	0	75 (58.6%)	141 (49.8%)	41 (45.6%)
	1	19 (14.8%)	62 (21.9%)	15 (16.7%)
	2	18 (14.1%)	24 (8.5%)	6 (6.7%)
	3	16 (12.5%)	56 (19.8%)	28 (31.1%)

MMSE = Mini-Metal Status Examination; CDR = Clinical Dementia Rating; ARWMC = Age-Related White Matter Changes.