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Viability of NTS of S. mansoni (mean ± SD) at 72 h of exposure in vitro to praziquantel (PZQ), artesunate (AS), or DMSO (vehicle) at 100 µM.
| % NTS Viability | |||||||
|---|---|---|---|---|---|---|---|
| Control (w/o DMSO) | Mean ± SD | Vehicle Control (DMSO) | Mean ± SD | PZQ | Mean ± SD | AS | Mean ± SD |
| 94.4 | 92.8 ± 6.6 | 69.4 | 92.4±10.0 | 34.8 | 50.0 ±23.9 | 0.0 | 87.5 ± 49.5 |
| 96.4 | 84.3 | 7.8 | 89.4 | ||||
| 95.3 | 96.4 | 52.0 | 87.5 | ||||
| 94.5 | 93.6 | 71.0 | 0.0 | ||||
| 100 | 100 | 50.0 | 93.8 | ||||
| 95.4 | 82.0 | ||||||
| 78.8 | 78.2 | ||||||
| 95.4 | 94.7 | ||||||
| 94.7 | 92.7 | ||||||
