Figure 6.

miR-192-5p and miR-584-3p influenced cell invasion ability of melanoma cells. (A) and (C): Migration and invasion ability were examined by Transwell assay in A2058 cells. After miR-192-5p, miR-584-3p mimics, or scramble control transfection for 24 h, cells were subjected to Transwell assay. Migrating and invading cells were stained with crystal violet solution. (B) and (D): Numbers of migrating or invading cells were quantified by counting three different fields under a phase-contrast microscope. The cell photographs from a representative experiment are depicted and the graph data were quantified using Ascent software. Data are reported as colonies compared with control (means ± SD).