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. 2019 Feb 21;9(2):75. doi: 10.3390/biom9020075

Table 1.

A summary of the research studies conducted on onions or onion extracts and their reported effects on testosterone.

(Onion or Onion Derivative) Dose (Mode of Treatment) Duration Population Effect on Testosterone Reference
Onion juice 2, 4, and 6 mL day−1 (Orally) 10 days Male albino rats (+) [20]
Onion juice 0.5 and 1 g rat−1 day−1 (Orally) 20 days Wistar male rats (+) [21]
Onion 15 mg kg−1 day−1 (Orally) 4 weeks Streptozotocin-induced diabetic (+) [22]
Onion juice 3 mL day−1 rat−1 (Orally) 4 weeks Lamotrigine-induced male rats (+) [23,24]
Aqueous extract of onion 1 mL of the extract/100 g of body weight
(Orally)
8 weeks Male rats with aluminum-induced reproductive toxicity (±) [25]
Aqueous extract of onion 1 and 2 mL rat−1 (Orally) 4 weeks Rats (±) [26]
Aqueous extract of onion 1 mL/100g of body weight (Orally) 4 weeks Male rats with cadmium-induced organ toxicity (±) [27]
Onion juice 1 and 2 mL day−1 rat−1 (Orally) 20 days Adult male abino rats (+) [28]
Onion juice 3 mL rat−1 (Orally) 60 days Eschericcia coli infected male rats (+) [29]
Onion juice 3 mL rat−1 (Orally) 60 days Permethrin-induced male rats (+) [30]
Onion juice 40 mg kg−1 (Orally) 14 days Testicular torsion/detorsion rat models (+) [31]
Onion extracts containing concentrated cysteine sulfoxides 30 mg day−1 (Orally) 14 days Healthy men (+) [17]

(+) Increase, (−) Decrease, (±) no effect.