Figure 1.

CCAAT/enhancer-binding protein β (C/EBPβ) expression in human lung cancer tissues. (A) Patients-derived lung cancer tissue arrays were examined for C/EBPβ expression using the immunoperoxidase method. Staining results were graded according to the intensity and proportion of positive area. Images were captured at a magnification of 200X by using the Aperio ImageScope software. Scale bars: 200 μm. (B) The histogram represents the percentage of the immunohistochemistry (IHC) score for C/EBPβ in 68 normal tissues, 95 primary, and 9 metastatic tumor tissues. The statistical significance was determined using the t-test, p < 0.05. (C) The association between C/EBPβ mRNA expression and overall survival of adenocarcinoma (whole dataset) and squamous cell carcinoma patients (GSE37745) was analyzed using the Kaplan–Meier Plotter. Hazard ratio (HR) significance was found with log-rank tests.