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. Author manuscript; available in PMC: 2019 Mar 8.
Published in final edited form as: Environ Pollut. 2018 Jun 5;241:511–520. doi: 10.1016/j.envpol.2018.05.055

Table 2.

Stereological measures of lungs of pre-/postnatally exposed mice and controls at P40.

Parameter Mean ± SD p
Exposed Control
Animal weight (g) 19.4 ± 1.6 18.5 ± 1.0 0.32
Lung volume (mm3) 92 ± 28 109 ± 10 0.22
vol/wt ratio (mm3·g−1) 4.7 ± 1.3 5.9 ± 0.7 0.11
ND of alveoli (103 mm−3) 9.73 ± 2.09 13.73 ± 1.08 0.005**
N of alveoli (106) 0.91 ± 0.38 1.51 ± 0.22 0.02*
V¯ of alveoli (103 μm3) 53.7 ± 10.0 39.2 ± 4.2 0.02*
Vf of alveoli (%) 50.8 ± 5.0 53.5 ± 2.6 0.33
Vf of alveolar septa (%) 39.5 ± 2.3 36.3 ± 3.2 0.11
Vf of airways (%) 6.7 ± 2.5 7.4 ± 2.9 0.68
Vf of vessels (%) 2.9 ± 1.6 2.8 ± 1.2 0.88
Vt of alveoli (mm3) 47.5 ± 17.1 58.5 ± 6.6 0.22
Vt of alveolar septa (mm3) 35.9 ± 9.6 39.8 ± 5.5 0.46
Vt of airways (mm3) 5.9 ± 2.4 8.1 ± 3.4 0.26
Vt of vessels (mm3) 2.5 ± 1.3 3.0 ± 1.3 0.56
SD of alveolar septa (mm−1) 192.5 ± 40.3 219.8 ± 24.3 0.23
SD of airways (mm−1) 18.5 ± 7.1 16.7 ± 1.5 0.59
SD of vessels (mm−1) 45.6 ± 13.4 61.1 ± 45.6 0.49
SA of alveolar septa (cm2) 184.5 ± 86.7 241.2 ± 40.1 0.22
SA of airways (cm2) 15.8 ± 5.4 18.3 ± 3.0 0.39
SA of vessels (cm2) 42.8 ± 21.5 67.7 ± 52.7 0.36

ND: number density, N: total number, V¯: mean volume, Vf: volume fraction, Vt: total volume, SD: surface density, SA: surface area.