Table 2.
Parameter | Mean ± SD | p | |
---|---|---|---|
Exposed | Control | ||
Animal weight (g) | 19.4 ± 1.6 | 18.5 ± 1.0 | 0.32 |
Lung volume (mm3) | 92 ± 28 | 109 ± 10 | 0.22 |
vol/wt ratio (mm3·g−1) | 4.7 ± 1.3 | 5.9 ± 0.7 | 0.11 |
ND of alveoli (103 mm−3) | 9.73 ± 2.09 | 13.73 ± 1.08 | 0.005** |
N of alveoli (106) | 0.91 ± 0.38 | 1.51 ± 0.22 | 0.02* |
of alveoli (103 μm3) | 53.7 ± 10.0 | 39.2 ± 4.2 | 0.02* |
Vf of alveoli (%) | 50.8 ± 5.0 | 53.5 ± 2.6 | 0.33 |
Vf of alveolar septa (%) | 39.5 ± 2.3 | 36.3 ± 3.2 | 0.11 |
Vf of airways (%) | 6.7 ± 2.5 | 7.4 ± 2.9 | 0.68 |
Vf of vessels (%) | 2.9 ± 1.6 | 2.8 ± 1.2 | 0.88 |
Vt of alveoli (mm3) | 47.5 ± 17.1 | 58.5 ± 6.6 | 0.22 |
Vt of alveolar septa (mm3) | 35.9 ± 9.6 | 39.8 ± 5.5 | 0.46 |
Vt of airways (mm3) | 5.9 ± 2.4 | 8.1 ± 3.4 | 0.26 |
Vt of vessels (mm3) | 2.5 ± 1.3 | 3.0 ± 1.3 | 0.56 |
SD of alveolar septa (mm−1) | 192.5 ± 40.3 | 219.8 ± 24.3 | 0.23 |
SD of airways (mm−1) | 18.5 ± 7.1 | 16.7 ± 1.5 | 0.59 |
SD of vessels (mm−1) | 45.6 ± 13.4 | 61.1 ± 45.6 | 0.49 |
SA of alveolar septa (cm2) | 184.5 ± 86.7 | 241.2 ± 40.1 | 0.22 |
SA of airways (cm2) | 15.8 ± 5.4 | 18.3 ± 3.0 | 0.39 |
SA of vessels (cm2) | 42.8 ± 21.5 | 67.7 ± 52.7 | 0.36 |
ND: number density, N: total number, : mean volume, Vf: volume fraction, Vt: total volume, SD: surface density, SA: surface area.