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. Author manuscript; available in PMC: 2019 Sep 27.
Published in final edited form as: Biotech Histochem. 2018 Sep 27;93(8):608–614. doi: 10.1080/10520295.2018.1514466

Figure 6.

Figure 6.

Secondary confirmation ex vivo using near infrared fluorescent imaging. Imaging demonstrated ex vivo increased probe accumulation within the breast tumor compared to the kidney, liver and spleen at 3 h. A) NIR-fluorescence evaluation of tumor, kidney, liver and spleen using the AMI system indicated that osteopontin-750 accumulated selectively within the breast tumor. B) ROI measurements on organs ex vivo were grouped by organ among three mice. Osteopontin-750 accumulation within the tumor was 4.6 × 109 (p = 0.0001) compared to the kidney (4.7 × 108), liver (2.5 × 108) and spleen (2.0 × 108).