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. Author manuscript; available in PMC: 2019 Sep 12.
Published in final edited form as: J Am Chem Soc. 2018 Aug 29;140(36):11424–11437. doi: 10.1021/jacs.8b06656

Figure 1.

Figure 1.

Chemical structures of the Plasmodium-selective proteasome inhibitors WLL-vs and the recently reported Carmaphycin B analog. EC50 values and selectivity index values are shown for each compound. HFF = human foreskin fibroblasts, and EC50 = half maximal effective concentration.