Fig. 7.

Structural features of CfERV-Fc1(a) proviruses. a Representation of the CfERV-Fc1(a)_CON provirus drawn to scale. Color usage of viral reading frames is consistent with that of [10]; ERV-Fc related gag and pol are shown in blue; the ERV-W related env is shown in orange. LTRs are colored in gray: U3 is in medium tone; R is dark; U5 is light. b Proviral structural features. When present, ORFs are indicated above the appropriate element. Insertions and deletions > 3 bases are depicted with blue and red flags, respectively. The env_∆1073 deletion is labeled and indicated by a dashed line, as are other truncated or deleted element features. Reference gaps present within are shown in light gray boxes to scale. Stop codons are indicated with a black or red asterisk, where red is used to specify premature stops common to two or more proviruses. Crosses at the left indicate proviruses that are unfixed among Canis samples. The number of substitutions between LTRs is shown at right with the calculated age as inferred based on the dog neutral substitution rate [44]