Table 1.
Levels of inflammatory cytokines and chemokines in the BAL fluid of mice from treatment groups
| Protein | Sal-Sal | Sal-ODE | OVA-Sal | OVA-ODE |
|---|---|---|---|---|
| TNF-α | 31.6 ± 11.8 | 471.0 ± 68.9* | 28.4 ± 11.5 | 223.7 ± 36.7*# |
| IL-6 | 21.8 ± 6.3 | 526.6 ± 91.7* | 24.0 ± 9.1 | 1068 ± 120.2*# |
| IL-4 | 1.5 ± 0.8 | 0.8 ± 0.4 | 3.3 ± 1.0* | 8.1 ± 3.2*# |
| IL-5 | 1.8 ± 0.6 | 2.8 ± 1.0 | 18.5 ± 7.8*# | 7.1 ± 2.1 |
| IL-13 | 0.1 ± 0.1 | 0.0 ± 0.0 | 14.6 ± 1.5*# | 16.7 ± 2.4*# |
| CCL2 | 9.1 ± 0.4 | 36.1 ± 11.9* | 14.5 ± 3.5 | 35.7 ± 17.2* |
| CCL3 | 15.0 ± 10.0 | 5493 ± 1065*% | 766.1 ± 339.7* | 4878 ± 1427 *% |
| CCL11 | 3.8 ± 0.5 | 7.0 ± 1.7 | 21.1 ± 5.9* | 14.2 ± 2.6 |
| CCL12 | 7.5 ± 0.3 | 10.0 ± 0.6 | 129.8 ± 55.3* | 231.2 ± 50.7*# |
| CCL22 | 13.5 ± 2.4 | 89.7 ± 35.7 | 295.0 ± 118.8* | 851.9 ± 272.3*# |
| CXCL1 | 71.5 ± 19.2 | 1336 ± 320.1* % | 144.7 ± 28.7 | 1037 ± 307.0* |
| CXCL2 | 33.5 ± 13.3 | 287.9 ± 60.3*% | 27.2 ± 14.51 | 197.0 ± 37.5*% |
Values (pg/ml) are mean ± standard error of mean. N = 4–8 mice/group
Statistical significance versus Sal-Sal denoted as *(p < 0.05); versus Sal-ODE denoted as #(p < 0.05) and bolded; versus OVA-Sal %(p < 0.05). IL-9, IL-17A, IL-17E, IL-33 and CCL8 were not detected