Table 3.

Summary of protein expression changes observed in immunohistochemistry of atypical astrocytes

Astrocyte marker	Time point
	Acute	4 hpi	1 dpi	3 dpi	7 dpi	14 dpi	28 dpi	56 dpi
GFAP	N/A	N/A	↓	N/A	↓	↓	N/A	N/A
Kir 4.1	N/A	↓	N/A	N/A	↓	↓	N/A	N/A
Glt1	↓	↓	↓	↓	↓	↓	↓	↓
GS	N/A	↓	N/A	N/A	↓	N/A	N/A	N/A
S100β	↓	↓	↓	↓	↓	↓	↓	↓
CX43	N/A	N/A	N/A	N/A	↓	N/A	N/A	N/A
Aldh1l1 eGFP	↓	↓	↓	↓	↓	↓	↓	↓
GCaMP5G	↓	N/A	↓	N/A	↓	N/A	N/A	N/A
IRES tdTomato	↑	↑	↑	N/A	↑	N/A	N/A	N/A
Aldh1l1 tdTomato	N/A	N/A	N/A	N/A	↑	N/A	N/A	N/A

Note that whereas GFAP was absent in atypical astrocytes, it was upregulated in other subsets of astrocytes after rdTBI.

N/A, Not applicable.