Figure 7.

Microdialysis results. A, Placement of probes on the border of the NAc shell and core at specific anterior–posterior coordinates. B, Raw NAc DA dialysate. Compared with rGT-trained rats, cued rGT-experienced animals showed significantly less basal efflux at baseline and after saline exposure, but comparable levels after cocaine administration. C, Change in DA efflux over baseline. All animals exhibited significant potentiation in DA release after cocaine exposure, but this effect was slightly greater in cued rGT-trained rats, indicating that, although these animals have a hypodopaminergic state at baseline, they may be slightly more reactive to cocaine. Data are mean of both left and right hemispheres ± SEM.