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. 2019 Feb 21;8(1):801. doi: 10.4102/ajlm.v8i1.801

TABLE 2.

Table detailing first-line, second-line and novel tuberculosis drugs, their resistance-associated genes and their length.

Drug Resistance associated Gene Length
Rifampicin rpoB 3519 bp
Isoniazid katG
inhA promoter (fabG1/mabA)
2223 bp
140 bp
Ofloxacin/Moxifloxacin gyrA
gyrB
2517 bp
2028 bp
Amikacin/Kanamycin rrs
eis promoter
1537 bp
36 bp
Pyrazinamide pncA /(pncA promoter) 561 bp (100 bp)
Bedaquiline11,23 atpE
Rv0678
246 bp
498 bp
Delamanid19 ddn
fgd1
456 bp
1011 bp

, The inhA and eis promoter regions were additionally annotated on the reference genome.