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Schematic structure of herpes simplex virus green-red (HSV-GR). The oncolytic HSV-GR was developed from a wild type strain. Modifications include deletion of both γ34.5 genes and insertion of a GFP and BleCherry expression cassette. CMVp, Cytomegalovirus promoter; BleCherry, bleomycin-mCherry fusion protein; pAs, polyadenylation signal; GFP, green fluorescent protein.
