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. 2018 Dec 4;21:51–67. doi: 10.1016/j.molmet.2018.11.012

Figure 4.

Figure 4

Drp1 pro-fission signaling is increased during acute exercise in muscle from trained female mice. (A) Quadriceps mRNA abundance (presented in a heat map), representing mitochondrial fission, fusion, and autophagy signaling, in SED, EX90, and TRN + EX90 (N = 6/group; one-way ANOVA with Tukey post hoc analysis). Muscles were harvested from both EX90 groups immediately following the cessation of exercise. (B–D) Quadriceps protein and phospho-protein representing mitochondrial fission, fusion, and autophagy signaling, in SED (open bars), EX90 (gray bars), and TRN + EX90 (black bars) (N = 6/group; representative immunoblots presented in Figures. 4B and S1; one-way ANOVA with Tukey post hoc analysis). Data are means ± SEM (N = 6/group). *, P < 0.05 vs. SED.