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. Author manuscript; available in PMC: 2019 Mar 8.
Published in final edited form as: Transpl Int. 2018 Jun 5;31(10):1164–1177. doi: 10.1111/tri.13273

Figure 2.

Figure 2

(a) Anti-pig non-Gal antibodies assessed by FCM. Line graphs show median fluorescence index that was calculated by intensity at each point postoperative day (30, 40, 50, 60, 70, 80, and 90)/pre-Tx level. All baboons had preformed anti-non-Gal Nabs, IgM, and IgG, prior to thymokidney (TK) Tx that were adsorbed by TKs after revascularization. Anti-pig antibody levels never exceeded above pre-Tx levels (index less than 1), indicating no elicited anti-pig antibodies, IgM and IgG, developed after TK Tx in both CTLA4-Ig-treated (a-1) and CTLA4-Ig-nontreated (a-2) groups. (b) Baboon recipient survival days after porcine TK Tx in CTLA4-Ig group (B393, B394, 14P5) and non-CTLA4-IG group (B363, B341, B366, B358).