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. Author manuscript; available in PMC: 2019 Mar 8.
Published in final edited form as: Transpl Int. 2018 Jun 5;31(10):1164–1177. doi: 10.1111/tri.13273

Table 1.

Description of Study Groups and Treatment Regimens.

Study group Baboon ID Xeno-organs Regimen
Study 1: Pilot study using available saved urine and kidney biopsy samples from three recipients of GalT-KO kidney
 Pilot study B289 Thymokidney Anti-CD154 mAb-based regimen
B314 Thymokidney Anti-CD154 mAb/rituximab-based regimen
B324 Kidney + BM
Study 2: Determine the effects of multiple doses of CTLA4-Ig treatment on the development of proteinuria following GalT-KO thymokidney transplantation in current (2013–2016) cases
 CTLA-4Ig group (2015–2016) B393 Thymokidney Weekly doses of CTLA-4Ig + anti-CD154 mAb/rituximab-based
B394 regimen
14P5
 Comp: non-CTLA4-Ig group (2013–2014) B341 Thymokidney Anti-CD154 mAb/rituximab-based regimen
B358
B363
B366