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. 2019 Mar 4;11:1997–2006. doi: 10.2147/CMAR.S195546

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© 2019 Song et al. This work is published and licensed by Dove Medical Press Limited

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Knockdown of hsa_circ_0000337 inhibits the proliferation, migration, and invasion of ESCC cells.

Notes: The CCK-8 and colony formation assay showed that knockdown of hsa_circ_0000337 inhibited proliferative activity in both (A) TE-1 and (B) KYSE-150 cell lines. The wound healing assay showed that knockdown of hsa_circ_0000337 suppressed the migration of (C) TE-1 and (D) KYSE-150 cell lines. The Transwell assay showed that knockdown of hsa_circ_0000337 inhibited the invasion of (E) TE-1 and (F) KYSE-150 cell lines. *P<0.05 and **P<0.01.

Abbreviations: CCK-8, Cell Counting Kit-8; ESCC; esophageal squamous cell carcinoma; NC, negative control.