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. 2019 Mar 4;2(Suppl 3):e000922. doi: 10.1136/bmjgh-2018-000922

Table 6.

Ratio of median prices between the bioequivalents and the referent in 2011 and 2016 shown as percentage (the difference between 2011 and 2016 is also shown)

Active pharmaceutical ingredient (1) Median price ratio BEQ:referent (2011) (2) Median price ratio BEQ:referent (2016) (3) Difference between ratio in 2016 and the ratio in 2011 (4)
Group 1
 Ciclosporin 85.7% 66.1% −19.6%
 Verapamil 46.1% 57.8% 11.7%
 Tacrolimus 81.9% 66.4% −15.5%
 Clomipramine 49.5% 45.7% −3.9%
 Acenocoumarol 38.7% 44.5% 5.8%
 Mycophenolate mofetil 59.3% 48.7% −10.6%
 Zidovudine BEQ not sold Referent not sold
Group 2
 Atorvastatin 56.1% 38.0% −18.0%
 Cefadroxil 86.4% 87.9% 1.5%
 Doxycycline 63.3% 57.9% −5.3%
 Losartan 47.4% 43.4% −4.0%
 Ketoprofen 34.9% 49.6% 14.7%
 Levothyroxine 48.0% 75.1% 27.1%
 Prednisone 50.4% Referent not sold
 Metformin 73.0% 76.2% 3.3%
 Clonazepam 71.2% 64.9% −6.3%

BEQ, bioequivalent.