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. 2019 Mar 5;8(1):1585163. doi: 10.1080/20013078.2019.1585163

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Differences in protein composition of EVs from unexposed or CSE-exposed BEAS-2B cells. (a) Histogram of p-values obtained by performing a moderated t-test to detect differences between control-EVs and CSE-EVs concerning the expression of proteins identified by nano-LC-MS/MS, n = 5. (b) Volcano plot. The x-axis shows the log2 of the fold change (expression in CSE-EVs/expression in control-EVs) and the y-axis shows the −log10 of the q-value. CSE: cigarette smoke extract.