| We evaluated the effect of food and liquid dispersion on the pharmacokinetics of BI 853520. |
| Only minimal effects of a high-caloric meal were found, and any effect on pharmacokinetics is unlikely to be clinically relevant; compared with a tablet formulation, administration as a liquid did not strongly affect the pharmacokinetics of BI 853520. |
| These properties may help make BI 853520 dosing more convenient and flexible, thereby improving treatment compliance. |
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