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. Author manuscript; available in PMC: 2019 Mar 8.
Published in final edited form as: Nat Biomed Eng. 2018 Jul 16;2(11):841–849. doi: 10.1038/s41551-018-0263-5

Figure 7. Pre-treatment with phage-MPs does not reduce functional efficacy of the treatment to clear bacteria from mouse lungs.

Figure 7.

Antibacterial efficacy of phage-MPs was examined in a mouse model of lung infection after 21 days of pre-treatment with phage-MPs or empty MPs with PA103. After 18 h of treatment, (a) bacterial load (n=4 mice/group, mean ± SD) and (b) phage load (n=4 mice/group, mean ± SD) in lung homogenate were quantified. Data were collected on both male wild-type C57BL/6 mice. One-way ANOVA followed by Tukey’s multiple comparison tests were used to detect statistical differences.