TABLE 2.
Variation of body composition by age and sex in patients with nonmetastatic CRC1
| SMM, cm2 | SMI, cm2/m2 | SMD, HU | VAT, cm2 | SAT, cm2 | TAT, cm2 | |
|---|---|---|---|---|---|---|
| Age, y | ||||||
| Males | ||||||
| <50 (n = 273) | 185.7 ± 30.6 | 59.2 ± 8.9 | 48.6 ± 8.0 | 153.9 ± 100.5 | 207.2 ± 130.3 | 369.3 ± 212.3 |
| 50–60 (n = 422) | 176.1 ± 28.4 | 56.6 ± 8.6 | 43.0 ± 8.1 | 188.2 ± 104.8 | 199.4 ± 117.3 | 399.0 ± 198.8 |
| 60–70 (n = 498) | 167.8 ± 28.6 | 53.5 ± 8.7 | 39.0 ± 8.5 | 224.1 ± 123.0 | 188.0 ± 96.2 | 426.4 ± 195.3 |
| 70–80 (n = 441) | 151.8 ± 26.2 | 49.4 ± 8.3 | 35.0 ± 9.0 | 217.2 ± 117.8 | 163.0 ± 77.6 | 397.2 ± 178.3 |
| P value2 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.04 |
| Females | ||||||
| <50 (n = 250) | 121.1 ± 20.7 | 45.6 ± 7.5 | 46.2 ± 8.6 | 72.9 ± 63.2 | 244.4 ± 136.6 | 324.5 ± 187.6 |
| 50–60 (n = 388) | 119.4 ± 20.1 | 45.4 ± 7.9 | 40.7 ± 8.6 | 111.1 ± 78.1 | 267.2 ± 140.2 | 388.9 ± 206.3 |
| 60–70 (n = 451) | 111.4 ± 19.8 | 42.5 ± 6.9 | 36.2 ± 8.8 | 121.9 ± 83.9 | 244.7 ± 127.0 | 380.9 ± 198.0 |
| 70–80 (n = 539) | 105.0 ± 17.5 | 40.8 ± 6.7 | 32.3 ± 8.9 | 116.2 ± 82.0 | 207.7 ± 111.5 | 340.6 ± 180.4 |
| P value2 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.66 |
| Age and sex interaction, P value3 | <0.001 | <0.001 | 0.27 | <0.001 | <0.001 | <0.001 |
1
Values are means ± SDs. CRC, colorectal cancer; HU, Hounsfield unit; SAT, subcutaneous adipose tissue; SMD, skeletal muscle radiodensity; SMI, skeletal muscle index; SMM, skeletal muscle mass; VAT, visceral adipose tissue; TAT, total adipose tissue.
2
Simple linear regression tests with age group as the predictor.
3
Likelihood ratio tests and multivariate linear regression models for interaction terms.