TABLE 3.
Multivariate completers’ analysis evaluating factors for severe oral mucositis1
| Variable | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Group | ||||||
| Glutamine | 0.32 (0.06, 1.62) | 0.167 | 0.30 (0.05, 1.67) | 0.169 | 0.44 (0.12, 1.60) | 0.212 |
| Placebo | 1.00 | 1.00 | 1.00 | |||
| Mean dose to oral cavity (per Gy) | 1.04 (0.97, 1.11) | 0.296 | 1.02 (0.96, 1.09) | 0.484 | 1.05 (0.99, 1.11) | 0.089 |
| Incidence of opioid use | ||||||
| Yes | 3.90 (0.73, 20.77) | 0.111 | 4.93 (0.79, 30.73) | 0.088 | 5.29 (1.38, 20.25) | 0.015 |
| No | 1.00 | 1.00 | 1.00 | |||
| BMI change (post-RT minus pre-RT), kg/m2 | 0.43 (0.22, 0.85) | 0.015 | 0.41 (0.20, 0.84) | 0.015 | — | |
| Gender | ||||||
| Male | — | 1.51 (0.06, 35.99) | 0.799 | 0.20 (0.01, 3.98) | 0.288 | |
| Female | — | 1.00 | 1.00 | |||
| Age, y | — | 0.95 (0.86, 1.04) | 0.241 | 1.01 (0.95, 1.07) | 0.839 | |
1
Multiple logistic regressions. RT, radiotherapy.