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. Author manuscript; available in PMC: 2019 Mar 8.
Published in final edited form as: Pharmacol Biochem Behav. 2017 Sep 15;161:47–52. doi: 10.1016/j.pbb.2017.08.013

Figure 2. Measurement of sucrose preference after induction of nicotine withdrawal in nicotinic KO mice.

Figure 2.

β2 and α6 KO and WT mice were chronically infused with nicotine (24 mg/kg/day) for 14 days. Minipumps were removed from mice on day 15, and sucrose preference (2%) was performed 48 hrs later. A) Sucrose preference test of β2 WT and KO mice at day 2 after removal of minipumps. B) Sucrose preference results of α6 WT and KO mice. Each point represents the mean ± S.E.M. of 8 mice per group. * Denotes p < 0.05 vs. Saline groups, # Denotes p < 0.05 vs. nicotine withdrawn WT mice.