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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Lancet HIV. 2019 Feb 5;6(3):e182–e190. doi: 10.1016/S2352-3018(18)30328-X

Table 3.

Scenario analysis: ICERs for POC EID compared to conventional EID.

POC

Conventional Pessimistic Intermediate Optimistic

Pessimistic $730 $760 $750
Intermediate $590 $720 $720
Optimistic Less effective, less expensive* Less effective, less expensive* $650

Abbreviations: ICER: incremental cost-effectiveness ratio, in $/year of life saved; POC: point-of-care; EID: early infant HIV diagnosis.

*

POC EID is less effective and less expensive compared to conventional EID.

**

Parameters varied in scenario analyses include EID uptake, result-return (time and probability), probability of ART initiation, assay sensitivity, specificity, and error rate (Appendix, p. 23). Full clinical and economic outcomes for all scenarios available in the Appendix, p. 24.