Figure 1.

Clinical, radiologic, histologic, and molecular features of three patients with primary intracranial pleomorphic sarcomas with myogenic differentiation and DICER1 mutation. a, Clinical features and pathogenic molecular alterations identified. b, Pre-operative T1-weighted post-contrast MR images. c, Representative images from H&E stained sections showing pleomorphic sarcomas with brisk mitotic activity and prominent eosinophilic cytoplasmic globules. d, Summary of reticulin staining and immunohistochemical results.