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qPCR analysis of Swiss male mice infected with bloodstream trypomastigotes of Colombiana strain (n=5) and submitted to co-administration therapy (Bz and VFV). VFV was diluted in 10 % DMSO plus 5 % Gum Arabic.
| % Negative blood qPCR* | Blood parasite load determined by qPCR | |
|---|---|---|
| Bz+VFV (simultaneous)** | 0 | 123 ± 53 |
| Bz | 0 | 13038 ± 13612 |
| VNI | 20 | 372 ± 528 |
| VFV | 0 | 905 ± 854 |
Surviving mice
Simultaneous therapy: 60 days of Bz + VFV (once a day)
