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. Author manuscript; available in PMC: 2020 Mar 8.
Published in final edited form as: ACS Infect Dis. 2019 Jan 23;5(3):365–371. doi: 10.1021/acsinfecdis.8b00253

Table 3 -.

PK profile data for VNI and VFV given from HPCD and DGAT formulations.

Compound Formulation Tmax, hours Cmax, μM [μg/mL] AUC, μg × h/L Life time, hoursa
VNI DGAT 2 39±2 [20] 163 16
HPCD 2 30±4 [15] 55 10
VFV DGAT 4 24±2 [11] 159 >26
HPCD 4 14±2 [8] 64 <24
a

Life time, hours: The time until compound becomes undetectable given by per oral route (below 0.1 μM, which is the detection limit). References: 4 and 22.