Table 1.
Patient No. | Recipient Sex | Donor Sex | Recipient -Donor HLA status | Preparation -Donor cell typea | Age | Diagnosis | Pregnancies (sons) | Days post-transplant | Cause of death |
---|---|---|---|---|---|---|---|---|---|
1 | Female | Male | Matched related | BM | 55 | Myeloma | 3 (3) | 21 | Diffuse alveolar damage, parainfluenza-3 pneumonia |
2 | Female | Male | Matched related | PBSC | 49 | Myeloma | ? (1) | 48 | Diffuse alveolar damage, hypertrophic cardiomyopathy |
3 | Female | Male | 1 Antigen MM related | PBSC | 56 | Myeloma | 4 (1) | 87 | Aspergillosis |
4 | Female | Male | 1 Antigen MM unrelated | BM | 39 | CML | ? (0) | 172 | Diffuse alveolar damage, varicella pneumonia |
5 | Female | Female | Matched unrelated | BM | 27 | ALL | 1 (0) | 20 | Fungal pneumonia |
6 | Female | Female | Matched unrelated | BM | 48 | AML | 2 (1) | 36 | Sinusoidal Obstruction Syndrome |
7 | Female | Female | Matched related | BM | 43 | AML | 3 (≥1) | 68 | Pseudomonas pneumonia |
8 | Female | Female | Matched related | BM | 39 | RAEB | 3 (≥1) | 74 | Aspergillosis, septicemia |
9 | Female | Female | Matched related | PBSCb | 63 | DLCL | 6 (≥1) | 83 | Aspergillus pneumonitis |
10 | Male | Male | Matched related | BM | 47 | RAEB | 83 | Congenital heart disease, central leukodystrophy |
All transplants were myeloablative, except where noted.
Nonmyeloablative.
BM bone marrow, PBSC peripheral blood stem cells, MM mismatched