Fig. 2. Cdyl^cKO male mice exhibited the progressive infertility.

a Testes harvested from Cdyl^Ctrl and Cdyl^cKO mice at 5 months. b Weight of body, testis, and epidydimis in Cdyl^Ctrl and Cdyl^cKO group (n = 6). c Pathology of Cdyl^cKO testis at 6 weeks, 14 weeks, and 5 months; Pathology of Cdyl^cKO epidydimis at 5 months. Bar = 200 μm. Bold arrow, loss of spermatogenic cells; arrow, Sertoli-cell-only syndrome phenotype; asterisk, hyperplasia of the interstitial tissues; arrowhead, seminal fluid in the lumen of epididymis. d Computer Assisted Semen Analysis of Cdyl^cKO males at 6 weeks and 5 months (n = 6). e Serum sex hormone levels of Cdyl^cKO males at 5 months (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001