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. 2019 Mar 8;9:3995. doi: 10.1038/s41598-019-40264-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Physiological role of E.coli diacylglycerol kinase (DGK) in recycling during the biosynthesis of membrane-derived oligosaccharides (MDOs)^1,2. MDOs are largely generated in response to environmental stress, such as low osmolarity^4,5. DGK is located within the inner membrane, where it catalyzes the ATP-dependent phosphorylation of potentially membrane-disruptive diacylglycerol (DAG) to non-toxic phosphatic acid (PA). It provides the basis for restoring phosphatidylglycerol (PG), which is consumed in the MDO cycle. The cartoon is based on the X-ray structure using the PDB ID 4UXX¹¹.