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. 2019 Mar 8;9:3927. doi: 10.1038/s41598-019-40406-y

Table 1.

Patient demographics of Group 1 & 2.

Group 1 & 2 (N = 30) Group 1 (N = 16) Group 2 (N = 14) P-value
Age at diagnosis of CNV (years) (range) 50.6 ± 10.1 (30–74) 51.7 ± 8.2 (39–67) 49.3 ± 12.2 (30–74) 0.61*
Gender (male: female) 23: 7 (3.3: 1) 11:5 (2.2:1) 12:2 (6:1) 0.26
Mean duration of follow-up (months) (range) 60.0 ± 53.4 (2.2–145.2) 77.3 ± 54.7 (9.3–145.2) 37.0 ± 42.0 (2.2–135.9) 0.02*
Systemic disease
   Diabetes mellitus, n (%) 4 (13.3) 2 (12.5) 2 (14.3) 0.65
   Hypertension, n (%) 10 (33.3) 7 (43.8) 3 (21.4) 0.18
Treated eye (Right: Left) 13:17 5:11 8:6 0.15
Duration from diagnosis of CSC to development of secondary CNV in Group 1 (months) (median) [range] N. A. 50.6 ± 50.3 (40.5)
[0.6–156.0]
N. A.
LogMAR BCVA at diagnosis of CNV 0.54 ± 0.50 0.48 ± 0.52 0.61 ± 0.49 0.28*

CNV = choroidal neovascularization; BCVA = best corrected visual acuity; N. A. = not applicable; logMAR = logarithm of minimal angle of resolution.

Group 1: Patients with secondary CNV in eyes with previous CSC.

Group 2: Patients diagnosed with CNV in eyes with putative chronic CSC beforehand.

*Statistical analysis with Mann-Whitney U tests between Group 1 & 2.

Statistical analysis with Fisher’s exact tests between Group 1 & 2.