Table 6.

Effect of pathological changes in cerebral cortex on focal cerebral ischemia reperfusion injury rat model ($\overline{x}$ ± s).

Group	Number	Dose (mg/kg)	—	+	++	+++
Sham operation group	14	–	14	0	0	0
Model group	9	–	0	0	2	7
Naoluotong group	10	20	2	5	2	1
Nimodipine group	11	500	3	5	2	1
High dose group	11	300	3	5	2	1
Middle dose group	11	150	2	4	4	1
Low dose group	10	75	1	3	4	2

From the regression analysis of the count data (Hu et al., 2018): *Compared with model group P < 0.05; **Compared with model group P < 0.01.

“–” Cerebral cortex is not edema, and the nerve cells are normal; “+” Cerebral cortex nerve cell edema, a small number of neuronal necrosis, the infarct area occupies less than 1/3 of cortex; “++” Cerebral cortex nerve cell edema, most neuronal necrosis, the infarct area occupies 1/3 ∼ 2/3 of cortex; “+++” Cerebral cortex nerve cell edema, most of the neuron necrosis, the infarct area occupies more than2/3 of cortex.