Fig. 2.

(A) Photomicrograph of untreated MCF-7 cells. Cells are polygonal or spindle-shaped and tightly packed. MCF-7 cells treated for 24 h with ethanolic seeds extracts. (B) 100 µg/mL, more cells are detached (become round or irregular instead of spindle shape), there is increase in intercellular spaces and there is increase of cell-free area. (C) 200 µg/mL, there are many irregularly shaped cells and increase in the intercellular space. (D) 300 µg/mL, almost all cells are shrinked, irregular round, losing their normal spindle shape morphology.