Fig. 3.

The stereochemical quality analysis of EGFR wildtype and mutant protein models by Procheck [Ramachandran plot – favored region is red in color; allowed region is yellow in color; disallowed region is white in color] and ProSa [overall model quality (black dots indicate the match between experimentally solved protein structures distinguished by dark blue (X-ray) and light blue (NMR); and residue model quality graphs (amino acid energies, +ve values regions are error part of the structure, whereas −ve value region considered to high structural quality)].