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. 2019 Jan 23;17(1):e66450. doi: 10.5812/ijem.66450

Table 2. The Result of the Generalized Additive Model on the Relationship of Body Mass Index with Thyroid Hormonesa,b,c.

TSH FT3 FT4
Mod0 Mod1 Mod0 Mod1 Mod0 Mod1
e.d.f 2.804 1.705 6.118 2.887 6.049 6.030
P 0.009 < 0.001 < 0.001 < 0.001 0.010 < 0.001

aThe level of complexity (nonlinearity) of each term of the model is determined by the estimated degrees of freedom (e.d.f.) of the smoother. An e.d.f. = 1 speaks of an almost linear relationship, while e.d.f. > 1 indicate a nonlinear relationship.

bMod0: Model of thyroid hormones and BMI.

cMod1: Model of thyroid hormones and BMI, Age, Sex (adjustment for age and sex).