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. 2019 Mar 9;19:35. doi: 10.1186/s12871-019-0705-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Relative blood flow velocity in middle cerebral artery during cardiopulmonary bypass. Blood flow velocity in the right middle cerebral artery (MCAV) was measured using transcranial Doppler sonography. Individual values, assessed during cardiopulmonary bypass (CPB) every 10 min, were normalized to the baseline value obtained before cannulation of the aorta and was termed MCAV_rel. Cerebral hyperperfusion was defined as relative MCAV > 100%. a Mean averaged MCAV_rel values for the no-POD group and the POD group, respectively. b Duration of cerebral hyperperfusion periods during CPB in the no-POD group and the POD group, respectively.Mean ± SD (boxes) and minimum and maximum (whiskers); n = 32 (no delirium) and n = 12 (delirium); unpaired, two-tailed Student’s t-test (b); * p < 0.05, *** p < 0.005