Table 5.

OS according to clinicophathological characteristics

	Mean OS (95% CI)a (months)	p-value
Overall	9.2 (5.3–13.2)
Age (years)
≤ 70	6.1 (0.3–11.8)	0.27
> 70	10.0 (7.2–12.8)
Gender
Male	8.9 (5.1–12.8)	0.76
Female	9.2 (2.3–16.1)
Histology
Adenocarcinoma	9.2 (4.6–13.9)	0.56
Squamous	9.8 (2.5–17.2)
PS ECOG
0	9.2 (5.6–12.8)	0.65
> 1	2.0 (0.1–5.4)
Smoke
Never smoker	9.9 (0.1–20.5)	0.80
Smoker	8.9 (4.7–13.2)
Prior treatment lines, n
1	6.1 (3.6–8.5)	0.036
≥ 2	12.2 (8.2–13.3)
RECIST response
No response	6.4 (4.8–8.0)	< 0.001
Response	13.5 (11.2–15.7)

^aMedian survival not reached