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. 2019 Mar 8;10:82. doi: 10.1186/s13287-019-1191-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Cellular characteristics of BMSCs. a Pipeline of this work. b Cell cycle analysis of BMSCs from passages 6 and 10 of in vitro expansion. c Apoptosis analysis of BMSCs from passages 6 and 10 of in vitro expansion. d Senescence of BMSCs from passages 6 and 10 of in vitro expansion. e Cytokine secretory level of BMSCs from passages 6 and 10 of in vitro expansion with (IR+) or without (IR−) irradiation. Data are represented as the mean ± SEM. Student’s t test was performed to compare P6 and P10 BMSCs with significance set at a P value of less than 0.05. *P < 0.05, **P < 0.01. The same letter (lowercase for P10 and uppercase for P6, respectively) indicates no significant difference among different post-irradiation time (Tukey HSD, P < 0.05)