Table 2.

Gene ontology functional enrichment of DMRs

GO ID	GO term	Ancestors	Direction	CpG 0	CpG 3	All
Biological process
GO:0032259	methylation	2	Hypo	Yes	Yes	Yes
Molecular function
GO:0003995	acyl-CoA dehydrogenase activity	4	Hypo	Yes	Yes	Yes

Table lists all significant terms identified in the Biological Process and Molecular Function categories with the ‘weight01’ algorithm, which accounts for GO term hierarchy. Genes of interest were tested against all genes, genes containing at least one methylated CpG and genes containing at least 3 methylated CpGs as per the DMR filtering of greater than 0 and 3 CpGs