Table 1.
Patient characteristics by group. IDH: isocitrate dehydrogenase. MGMT: O6-methylguanine DNA methyltransferase. SD: standard deviation. SEM: standard error of the mean.
| Patient Characteristics | |||
|---|---|---|---|
| Neoadjuvant (n=16) |
Adjuvant (n=16) |
Total (n=32) |
|
| Demographics | |||
| Age at enrollment - years, mean ± SD | 55.4 ± 13.5 | 59.3 ± 12.3 | 57.4 ± 12.8 |
| Gender, no. (%) | |||
| Male | 7 (44) | 5 (31) | 12 (38) |
| Female | 9 (56) | 11 (69) | 19 (63) |
| Karnofsky performance status, mean ± SD | 80 ± 8.9 | 86 ± 6.2 | 83 ± 8.2 |
| Steroid use at registration | |||
| No. of patients receiving steroids | 7 | 7 | |
| Daily dosage, median, mg/day (range) | 0 (0-4) | 0 (0-6) | |
| MGMT status, no. (%) | |||
| Methylated | 6 (38) | 11 (69) | 17 (53) |
| Unmethylated | 7 (44) | 4 (26) | 11 (34) |
| Unknown | 3 (19) | 1 (6) | 4 (13) |
| IDH status, no. (%) | |||
| Wild-type | 12 (75) | 13 (81) | 25 (78) |
| Mutant | 3 (19) | 2 (13) | 5 (16) |
| Unknown | 1 (6) | 1 (6) | 2 (6) |
| Pre-surgery tumor volume, cm3, mean ± SEM | 21.8 ± 6.2 | 18.9 ± 3.2 | |