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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Exp Cell Res. 2019 Feb 19;377(1-2):109–114. doi: 10.1016/j.yexcr.2019.02.017

Fig 2: Engineered materials with tunable biophysical and biochemical matrix properties.

Fig 2:

(a). Illustration of biological matrices such as collagen gels and Matrigel™ where changes in polymer density to vary mechanical properties invariably alter adhesive site density and organization through changes to fiber structure and density. (b,c) Illustration of independent control of polymer density and adhesive ligand density in multi-armed PEG-based hydrogels. (b) Changes in adhesive ligand density is independent of polymer density; conversely, (c) changes in polymer density to vary mechanical properties does not alter adhesive ligand density and organization. Created with BioRender.