Table 5.

Estimated annual rates of cognitive change (z-score units) across groups

	Verbal Learning & Memory	Speed & Flexibility
Hypertension	β [95% CI]	β [95% CI]
Aβ−/HTN−	−0.039 [−0.083, 0.005]	0.002 [−0.037, 0.041]
Aβ+/HTN−	−0.043 [−0.089, 0.002]	−0.011 [−0.051, 0.029]
Aβ−/HTN+	−0.033 [−0.083, 0.017]	−0.001 [−0.044, 0.042]
Aβ+/HTN+	−0.091 [−0.150, −0.032]	−0.020 [−0.073, 0.032]
Obesity
Aβ−/OB−	−0.043 [−0.089, 0.002]	0.005 [−0.035, 0.045]
Aβ+/OB−	−0.038 [−0.084, 0.009]	−0.010 [−0.051, 0.030]
Aβ−/OB+	−0.032 [−0.077, 0.013]	0.001 [−0.039, 0.040]
Aβ+/OB+	−0.082 [−0.134, −0.030]	−0.014 [−0.059, 0.031]
Depression
Aβ−/DEP−	−0.038 [−0.082, 0.007]	−0.0001 [−0.039, 0.038]
Aβ+/DEP−	−0.056 [−0.102, −0.011]	−0.014 [−0.053, 0.026]
Aβ−/DEP+	−0.067 [−0.127, −0.006]	−0.030 [−0.085, 0.025]
Aβ+/DEP+	−0.028 [−0.102, 0.046]	−0.035 [−0.095, 0.025]

Aβ=beta-amyloid; HTN=hypertension; OB=obesity; DEP=depression